Epub 2018 Nov 21. Limited information on the long-term course of PE patients is available so far. In case a patient returned an incomplete questionnaire, a study collaborator contacted the patient by telephone to complete all missing items. Dimension scores were then transformed to a scale from 0–100 to make them comparable across dimensions, with higher scores indicating worse outcome. 10.1111/j.1538-7836.2007.02489.x, Article  This site needs JavaScript to work properly. Health Qual Life Outcomes 12, 174 (2014). All item-total correlation values were >0.2, ranging from 0.53 to 0.92 (data not shown for individual items). PubMed Google Scholar. The French version of the PEmb-QoL showed good reliability (internal consistency, item–total and inter-item correlations), reproducibility (test-retest reliability), and validity (convergent, discriminant) in French-speaking patients with PE. It covers six health dimensions: frequency of complaints, activities of daily living limitations, work-related problems, social limitations, intensity of complaints, and emotional complaints. Intra-class correlation coefficients for the test-retest analysis were high, ranging between 0.85 for social limitations and 0.96 for emotional complaints (Table 5). doi: 10.1056/NEJMcp0804570. Participants were then mailed a second PEmb-QoL and SF-36 questionnaire ten days after the baseline evaluation. Radiology 1992, 185: 381–387. Quality of life and functional limitations after pulmonary embolism and its prognostic relevance. Recently, the Pulmonary Embolism Quality of Life (PEmb-QoL) Questionnaire has been developed to address this gap. 2019 Nov;17(11):1923-1934. doi: 10.1111/jth.14589. EQ-5D-5L was 0.89±0.12 3 weeks after enrolment and improved to 0.91±0.12 at 3 months (p<0.0001). MR and MM collected the data. When correlating the PEmb-QoL and the SF-36 dimensions, we found a particularly strong correlation between activities of daily living limitations and physical functioning, and between work-related problems and physical role functioning. Given that patients in our cohort were older (63 vs. 56 years) and less likely to have cardiopulmonary comorbidity (13% vs. 20%) and obesity (13% vs. 39%) than patients in the study by Klok et al. This overall score met standard criteria of acceptability, reliability, reproducibility, and validity for use as a summary patient-reported measure of outcome in patients with acute PE. 10.1001/archinternmed.2007.69, PubMed Central  Background Early discharge of patients with acute low-risk pulmonary embolism (PE) requires validation by prospective trials with clinical and quality of life outcomes. Thromb Res 2013, 132: 500–505. We identified consecutive patients aged >18 years with an acute, objectively confirmed PE admitted at the emergency department of the Lausanne university hospital, Switzerland, from August 1, 2009 to September 30, 2011 using the hospital’s electronic patient tracking system. The PEmb-QoL dimension and overall summary scores were only weakly correlated with clinical characteristics, indicating a good discriminant validity (Table 7). Patient Prefer Adherence. The transformed PEmb-QoL dimension scores were depicted in a box plot as medians with interquartile range (IQR). Originally developed in Dutch and English, we sought to prospectively validate the psychometric properties of a French version of the PEmb-QoL. The development and validation of the Cluster Headache Quality of life scale (CHQ). Baseline characteristics were shown as proportions or medians and ranges, as appropriate. The PEmb-QoL is a validated 40-item questionnaire to quantify health-related quality of life in patients having experienced pulmonary embolism (PE). Acute venous thromboembolism (VTE), defined as deep vein thrombosis (DVT) and/or pulmonary embolism (PE), is common and has a high impact on morbidity, mortality, and costs of care [1],[2]. The PEmb-QoL is a validated 40-item questionnaire to quantify health-related quality of life in patients having experienced pulmonary embolism (PE). Almost all Cronbach’s alpha coefficients were >0.9 except one (intensity of complaints, 0.7), indicating high internal consistency (Table 4). Because both questionnaires were developed to assess health-related quality of life, we assumed that the two measures would be correlated in a moderate range, one being a disease-specific and the other a generic health-related quality of life questionnaire. Epub 2016 Sep 5. . This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. I. conceptual framework and item selection. Most people can walk and do light housework right away after a pulmonary embolism, but you may get tired easily or feel short of breath. Although clinical trials have demonstrated short-term benefit of catheter-based therapies to improve right ventricular (RV) dysfunction following acute pulmonary embolism (PE), 1–4 a paucity of data regarding long-term RV remodeling, functional status, and quality of life exists to guide integration of these revascularization strategies into evidence-based clinical practice. For those that survive the pulmonary embolism there is the possibility of decreased life expectancy and the development of complications that can impair quality of life. We decided that a time period of ten days between the repeated distributions of the questionnaires was long enough to prevent recall bias but short enough to ensure that a clinical change in the symptoms being measured was unlikely to occur. 2004;350:2257–2264. Our factor analysis supported the formation of three dimensions: limitations in daily activity (items 4b-m, 5a-d), symptoms (items 1a-h and 7), and emotional complaints (items 9a-f and j). J Clin Epidemiol 2006, 59: 1049–1056. Article  Validation and psychometric properties of the Maltese version of the Duke Anticoagulation Satisfaction Scale (DASS). Life After a Pulmonary Embolism Having a pulmonary embolism (PE) can be a shocking and traumatic experience. Patients with a prior history of pulmonary embolism (PE) were identified from the thrombosis registry at Østfold Hospital Trust, Fredrikstad, Norway. 2004;164:17–26. COVID-19 is an emerging, rapidly evolving situation. It covers six health dimensions: frequency of complaints, activities of daily living limitations, work-related problems, social limitations, intensity of complaints, and emotional complaints. Recently, a large group of patients with persistent dyspnea, poor physical capacity, and reduced health-related quality of life (HRQoL) following pulmonary embolism (P Cite this: Addressing quality-of-life issues after an acute pulmonary embolism - Medscape - Jul 30, 2010. Rationale: There is a lack of information on the long-term prognosis of patients with acute pulmonary embolism (PE).. We could not exclude the possibility that the Likert scale used did not have a large enough range to accommodate the distribution of the data or that there was a social desirability bias (i.e., patients thought it made them look better if they reported high quality of life). Besides the transient discomfort related to acute VTE, health-related quality of life is substantially influenced by the development of VTE-related complications [3]. We regarded an item-total correlation >0.2 and an average inter-item correlation >0.3 as good [23]. Indeed, floor effects >15% were also observed in all six dimensions in the Norwegian version of the PEmb-QoL [10]. Go to follow-up appointments and take blood thinners as directed. See this image and copyright information in PMC. 10.1097/00007632-200012150-00008, Article  Recently, a disease-specific instrument for assessing QoL after PE, called the Pulmonary Embolism Quality of Life (PEmb-QoL), has been developed and validated. Frey PM, Méan M, Limacher A, Leiss W, Schwab N, Rochat M, Aujesky D. Thromb Res. In a second step, we averaged these transformed scores (except items Q2 and Q3) to obtain an overall summary score. As described in the initial publication [8], the PEmb-QoL dimension scores were calculated by taking the mean of the constituting items. Blood. Konstantinides S: Acute pulmonary embolism. https://doi.org/10.1186/s12955-014-0174-4, DOI: https://doi.org/10.1186/s12955-014-0174-4. The impact on RV remodeling, functional status, and quality of life over the long-term remains unclear. The factor analysis presented by Klok et al. Google Scholar, Rosendaal FR, Van Hylckama Vlieg A, Doggen CJM: Venous thrombosis in the elderly. Pulmonary embolism quality of life (PEmb-QoL) questionnaire PEmb-QoL is a disease-specific questionnaire, devel-oped to assess QoL in patients with PE [19]. Acute venous thromboembolism (VTE), defined as deep vein thrombosis (DVT) and/or pulmonary embolism (PE), is common and has a high impact on morbidity, mortality, and costs of care [1,2].Besides the transient discomfort related to acute VTE, health-related quality of life is substantially influenced by the development of VTE-related complications []. To cite this article: Cohn DM, Nelis EA, Busweiler LA, Kaptein AA, Middeldorp S. Quality of life after pulmonary embolism: the development of the PEmb-QoL questionnaire. Rochat, M., Méan, M., Limacher, A. et al. Ware JE Jr, Kosinski M, Dewey JE: How to score - Version 2 of the SF-36 Health Survey (Standard and Acute Forms). Objectives: To assess the long-term risk for adverse events after PE.. Methods: Consecutive patients diagnosed with PE between January 2001 and July 2007, and patients in whom PE was ruled out from a previous study were followed until July 2008 for the occurrence of … -, Kahn SR, Ginsberg JS. In a first step, we transformed all item scores to a scale ranging from 0 to 100. Depending on the underlying cause of the pulmonary embolism, patients remain on anticoagulation medication for several weeks to months after treatment to prevent clots from redeveloping, with periodic checkups for incidence of bleeding. Thus, we could not entirely exclude the possibility that elderly and sicker patients were underrepresented in our study. Quality of life after pulmonary embolism: validation of the … It is dangerous because almost a quarter of pulmonary embolism cases present as sudden death and up to a third of pulmonary embolism will ultimately be fatal. The median (range) time between occurrence of the index PE and study enrollment was 15 (5–23) months. We chose a sample size of 100 patients to validate the French version of the PEmb-QoL questionnaire, which is in accordance with methodological recommendations [14],[15] and a previous similar validation study [16]. It is well known that measurement properties of QoL questionnaires adapted for a different population may differ from their original version due to differing translational, cultural, and methodological factors [11],[21],[24]. [8], we could not exclude the possibility that these differences in patient baseline characteristics did not contribute to differences in self-reported health measures. Summary. BACKGROUND: Even though quality of life (QoL) has become a key component of medical care, there is no instrument available that specifically measures QoL after pulmonary embolism (PE). Part of [8] and might be explained by the fact that these dimensions focus on the extent of limitations when performing work or physical exercises. A similar approach was used in previous studies examining discriminant validity of a similarly structured quality of life questionnaire for DVT [6],[16]. Spine (Phila Pa 1976) 2000, 25: 3130–3139. 10.1111/j.1538-7836.2009.03341.x, Klok FA, Cohn DM, Middeldorp S, Scharloo M, Buller HR, van Kralingen KW, Kaptein AA, Huisman MV: Quality of life after pulmonary embolism: validation of the PEmb-QoL Questionnaire. N Engl J Med 2004, 350: 2257–2264. Acute venous thromboembolism (VTE), defined as deep vein thrombosis (DVT) and/or pulmonary embolism (PE), is common and has a high impact on morbidity, mortality, and costs of care [1,2].Besides the transient discomfort related to acute VTE, health-related quality of life is substantially influenced by the development of VTE-related complications []. Bern Open Repository and Information System, Konstantinides S. Acute pulmonary embolism. Question 4a (‘Do your lung symptoms now limit you in daily activities at work?’) was omitted from the factor analysis because almost half of patients in our sample did not work. Thus, the French version of the PEmb-QoL can be used with confidence in prospective studies to assess PE-specific quality of life and symptoms. Background: Even though quality of life (QoL) has becomeakeycomponentofmedicalcare,thereisnoinstrument available that specifically measures QoL after pulmonary embolism (PE). In contrast, a substantial floor effect was present in five out of six PEmb-QoL dimensions, i.e. 10.1001/jama.1990.03440200057023, Remy-Jardin M, Remy J, Wattinne L, Giraud F: Central pulmonary thromboembolism: diagnosis with spiral volumetric CT with the single-breath-hold technique—comparison with pulmonary angiography. Because no French version of this questionnaire is available, we performed a forward-backward translation from the English version of the PEmb-QoL questionnaire into French according to previous published recommendations [11]. In the Norwegian version of PEmb-QoL questionnaire, an exploratory factor analysis using a different criterion to determine the number of underlying dimensions (Eigenvalues >1) resulted in six new dimensions that were not identical with the original version [10]. To facilitate the comparison of PE-related quality of life across studies, we created an overall PEmb-QoL summary score using all items, except Q2 (“At what time of day are your lung symptoms most intense?”) and Q3 (“Compared to one year ago, how would you rate the condition of your lungs in general now?”), which were never scored. NIH [8] already observed such floor and ceiling effects in some of the PEmb-QoL dimensions, we presumed that the floor and ceiling effects were not specifically related to the French version of the PEmb-QoL questionnaire. 10.1007/s11136-004-5742-3, Cattell RB: The scree test for the number of factors. Springer Nature. While items 9 g-i (Burden to family and friends, Afraid to exert yourself, Limited in taking a trip) were expected to cluster in the dimension “emotional complaints”, they clustered in “limitations in daily activity” in our study. A complication of DVT in legs and arms is pulmonary embolism (PE). Validating the Chinese version of the PEmb-QoL questionnaire: A measure for quality of life assessment after pulmonary embolism. J Clin Epidemiol 2007, 60: 34–42. J Thromb Haemost 2009, 7: 1044–1046. Would you like email updates of new search results? A study using the Dutch version of the PEmb-QoL found that patients with PE had an impaired quality of life compared to the age-matched general population [9]. Dyspnea, quality of life and walking capacity during 1 year follow-up after a first episode of pulmonary embolism: results of the E.L.O.P.E. -. The scores vary from 0 to 100 for each dimension, with higher values indicating better health [18],[19]. Background: Background We aimed to evaluate health-related quality of life (QOL), dyspnea, and functional exercise capacity during the year following the diagnosis of a first episode of pulmonary embolism. doi: 10.1001/archinte.164.1.17.  |  J Clin Epidemiol 1998, 51: 1013–1023. Summary. Responses are rated on a Likert response scale. Introduction. Box plot of PEmb-QoL dimension and summary scores. Given that Klok et al. It is dangerous because almost a quarter of pulmonary embolism cases present as sudden death and up to a third of pulmonary embolism will ultimately be fatal. The study was stopped for efficacy after … Standardized dimension and summary scores of the SF-36 questionnaire were calculated using the U.S. 1998 reference population [20]. Abu Bakar N, Torkamani M, Tanprawate S, Lambru G, Matharu M, Jahanshahi M. J Headache Pain. Cite this article. NLM Background: We aimed to evaluate health-related quality of life (QOL), dyspnea, and functional exercise capacity during the year following the diagnosis of a first episode of pulmonary embolism. Recently, the Pulmonary Embolism Quality of Life (PEmb‐QoL) Questionnaire has been developed to address this gap. Quality of life after pulmonary embolism: validation of the PEmb-QoL Questionnaire. Additional file 1: The French version of the PEmb-QoL questionnaire. Riva N, Borg Xuereb C, Makris M, Ageno W, Gatt A. 10.1111/j.1538-7836.2008.03002.x, Department of Internal Medicine, Lausanne University Hospital, CHUV, Rue du Bugnon 46, Lausanne, 1011, Switzerland, Division of General Internal Medicine, Bern University Hospital, Bern, Switzerland, Department of Clinical Research, and Institute of Social and Preventive Medicine (ISPM), CTU Bern, University of Bern, Bern, Switzerland, Emergency Department, Lausanne University Hospital, Lausanne, Switzerland, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands, Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands, You can also search for this author in Overall, 41 participants (40%) answered ‘I do not work’ for the question Q4a. Recently, the Pulmonary Embolism Quality of Life (PEmb-QoL) Questionnaire has been developed to address this gap. QualityMetric, Incorporated, Lincoln, Rhode Island; 2001. Improvement was consistent across all PEmb-QoL dimensions. statement and Clipboard, Search History, and several other advanced features are temporarily unavailable. N Engl J Med 2008, 359: 2804–2813. Only one dimension, work related problems, had a substantial ceiling effect, with 18% of patients scoring the maximum score (lowest possible quality of life) in this dimension. Methods The multinational Home Treatment of Pulmonary Embolism (HoT-PE) single-arm management trial investigated early discharge followed by ambulatory treatment with rivaroxaban. The relatively strong correlation between emotional complaints and social and emotional role functioning and mental health did not come as a surprise, either. Thromb Res. We used the principal factor method to analyze the correlation matrix and applied an orthogonal varimax rotation on the loading matrix. 2008;168:425–430. These are especially important if you were discharged home from the emergency department. 2015; 126 : 750 View in Article 10.1207/s15327906mbr0102_10. By using this website, you agree to our French-speaking consecutive adult patients with an acute, objectively confirmed PE admitted to the emergency department of a Swiss university hospital between 08/2009 and 09/2011 were recruited telephonically. For those that survive the pulmonary embolism there is the possibility of decreased life expectancy and the development of complications that can impair quality of life. Recently, a Norwegian version of the PEmb-QoL was successfully validated [10]. Multivariate Behav Res 1966, 1: 245–276. ratio in massive and submassive pulmonary embolism. Thus, the French version of the PEmb-QoL questionnaire met standard criteria of reliability and validity for use as a patient-reported measure of outcome in patients with PE, as previously shown for the Dutch version of the questionnaire. Med Care 1992, 30: 473–483. The correlation between intensity of complaints and bodily pain was clinically also plausible. 10.1148/radiology.185.2.1410342, Terwee CB, Bot SD, de Boer MR, van der Windt DA, Knol DL, Dekker J, Bouter LM, de Vet HC: Quality criteria were proposed for measurement properties of health status questionnaires. Recently, the Pulmonary Embolism Quality of Life (PEmb‐QoL) Questionnaire has been developed to address this gap. The median PEmb-QoL dimension and overall summary scores are shown in Figure 1. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. 2018 Jun;166:86-91. doi: 10.1016/j.thromres.2018.04.020. eCollection 2019. Quality of life after pulmonary embolism: validation of the French version of the PEmb-QoL questionnaire. Overall, these correlations supported a good convergent validity. OH, FAK, and DMC critically revised the manuscript. Quality of life after pulmonary embolism: the development of the PEmb-QoL questionnaire. eCollection 2019. item 6 (Interference with normal social activities) in symptoms and items 8 (Intensity of breathlessness) and 9 g-i (Burden to family and friends, Afraid to exert yourself, Limited in taking a trip) in limitations in daily activity. Altman DG: Practical statistics for medical research. PEmb-QoL dimensions were moderately well correlated between themselves (0.53 ≤ r ≤0.83), with the highest correlation being between intensity of complaints and frequency of complaints (r = 0.83) and between intensity of complaints and emotional complaints (r = 0.75). A pulmonary embolism (PE) is the sudden blockage of a blood vessel in the lungs by an embolus. Background: Even though quality of life (QoL) has become a key component of medical care, there is no instrument available that specifically measures QoL after pulmonary embolism (PE). French-speaking consecutive adult patients with an acute, objectively confirmed PE admitted to the emergency department of a Swiss university hospital between 08/2009 and 09/2011 were recruited telephonically. Pulmonary embolism (PE) occurs in 600,000 to 1 million individuals each year, and has a 15% 1-year mortality, making it ... limitation, and impaired quality of life that persist for longer than 3 months after effective anticoagulation for acute PE. However, less than a third of patients had to be contacted because they had one or more missing items. PubMed  Introduction. Background: Even though quality of life (QoL) has become a key component of medical care, there is no instrument available that specifically measures QoL after pulmonary embolism (PE). To our knowledge, studies evaluating the quality of life (QoL) in patients with a history of acute pulmonary embolism (PE) are not available, even though QoL is a key outcome component of medical care and a predictor of disease-specific prognosis. All questionnaires were returned by participants (response rate 100%). We used standard psychometric tests and criteria to evaluate the acceptability, reliability, and validity of the French version of the PEmb-QoL. In addition to dealing with what can be a very painful condition, you may also feel scared about how it could affect your health and worried that it could happen again. First, only 42% of potentially eligible persons with PE completed the questionnaires, mostly, because they were unreachable or refused to participate. The PEmb-QoL is a validated 40-item questionnaire to quantify health-related quality of life in patients having experienced pulmonary embolism (PE). [8] did not explore the appropriate number of latent factors (underlying dimensions) but rather sought to confirm the pre-specified structure of the questionnaire based on six dimensions, we explored the number of underlying dimensions and grouping of items in an exploratory factor analysis. Objective: To evaluate the validity of the PEmb-QoL questionnaire. It covers six domains: frequency of complaints (eight items), activities of daily life (ADL) limitations (13 items), work-related problems (four items), social limitations (one item), inten- We contacted 33 participants (32%) by phone to complete missing items. Privacy Methods: This was a prospective multicenter cohort study of 100 patients with acute pulmonary embolism recruited at 5 Canadian hospitals from 2010-2013. Lamping DL, Schroter S, Kurz X, Kahn SR, Abenhaim L: Evaluation of outcomes in chronic venous disorders of the leg: development of a scientifically rigorous, patient-reported measure of symptoms and quality of life. Epub 2019 Aug 13. Methods: Patients with a prior history of pulmonary embolism (PE) were identified from the thrombosis registry at Østfold Hospital Trust, Fredrikstad, Norway. Introduction. PubMed  We did a correlation analysis using SF-36 component scores to assess convergent validity of the PEmb-QoL dimension and overall summary scores. Kahn SR, Lamping DL, Ducruet T, Arsenault L, Miron MJ, Roussin A, Desmarais S, Joyal F, Kassis J, Solymoss S, Desjardins L, Johri M, Shrier I: VEINES-QOL/Sym questionnaire was a reliable and valid disease-specific quality of life measure for deep venous thrombosis. The aim of the study was to assess the 12-month illness burden in terms of health-related quality of life (HrQoL) and mortality, in relation to differences in patient characteristics. Below are the links to the authors’ original submitted files for images. Background: Early discharge of patients with acute low-risk pulmonary embolism (PE) requires validation by prospective trials with clinical and quality of life outcomes. Most patients can maintain a good quality of life after treatment. However, our enrolment rate compared well with previous studies, in which less than 40% of screened patients with VTE underwent quality of life assessments [10],[25]. The exploratory factor analysis suggested three underlying dimensions: limitations in daily activity (items 4b-m, 5a-d), symptoms (items 1a-h and 7), and emotional complaints (items 9a-f and j). Google Scholar, Kahn SR, Ginsberg JS: Relationship between deep venous thrombosis and the postthrombotic syndrome. 2014 Dec 3;12:174. doi: 10.1186/s12955-014-0174-4. Terms and Conditions, All dimensions had floor effects, ranging from 13% for emotional complaints (Q9) to 66% for social limitations (Q6) (Table 2). J Thromb Haemost 2009; 7: 1044–6. • Lower QoL in patients after acute PE vs. DVT alone • especially on the subscales physical quality of life and mental fatigue 1. Factor analysis is widely used to evaluate whether questionnaire items can be grouped into clusters representing different dimensions of the construct under study [21]. Health Qual Life Outcomes. Given that items 6, 8, 9 g, and 9i did not have the highest loadings in the original version of the PEmb-QoL either, a possibility would be to remove items 6, 8, 9 g, and 9i and to replace the original six dimensions by three dimensions in the French version of the questionnaire. The PEmb-QoL, originally developed in Dutch and translated into English, is a 40-item questionnaire that measures the impact of PE on quality of life from the patient’s perspective over the past four weeks [7],[8]. The confirmation of PE was based on either a high-probability ventilation-perfusion lung scan or a positive computed tomography scan [12],[13]. The PEmb-QoL questionnaire contains nine questions (40 items) covering six dimensions: frequency of complaints (Q1, 8 items), activities of daily living limitations (Q4, 13 items), work-related problems (Q5, 4 items), social limitations (Q6, 1 item), intensity of complaints (Q7 and Q8, 1 item each), and emotional complaints (Q9, 10 items). 2020 Jan-Feb;18(1):107-119. doi: 10.1080/15402002.2018.1546178. Google Scholar, Cohn DM, Nelis EA, Busweiler LA, Kaptein AA, Middeldorp S: Quality of life after pulmonary embolism: the development of the PEmb-QoL questionnaire. As an alternative, items 6, 8, 9 g-i could be grouped into the dimension on which they loaded highest, i.e. Chest 2010;138:1432–40. Background: Most pulmonary embolism (PE) research has focused on outcomes such as mortality and PE recurrence.Patient-centered outcomes such as persistent dyspnea, impaired quality of life (QOL) and reduced walking capacity after PE have been largely unstudied. Qual Life Res 2005, 14: 1203–1218. After rotation, the three factors accounted for 35%, 22%, and 19% of the total variance, respectively. Aaronson N, Alonso J, Burnam A, Lohr KN, Patrick DL, Perrin E, Stein REK: Assessing health status and quality-of-life instruments: attributes and review criteria. The French version of the PEmb-QoL showed good reliability (internal consistency, item-total and inter-item correlations), reproducibility (test-retest reliability), and validity (convergent, discriminant) in French-speaking patients with PE. The Pulmonary Embolism Quality of Life questionnaire (PEmb-QoL) is a 40-item questionnaire to measure health-related quality of life in patients with … Lebrun C, Gély-Nargeot MC, Maudarbocus KH, Bayard S. Behav Sleep Med. 2019 Aug 28;12:741-752. doi: 10.2147/PRBM.S216617. Background Early discharge of patients with acute low-risk pulmonary embolism (PE) requires validation by prospective trials with clinical and quality of life outcomes. Google Scholar, PIOPED The Investigators: Value of the ventilation/perfusion scan in acute pulmonary embolism: results of the prospective investigation of pulmonary embolism diagnosis (PIOPED) JAMA 1990, 263: 2753–2759. To assess PE-specific quality of life in patients after acute PE vs. DVT alone especially... Intensity of complaints and social and emotional role functioning and mental fatigue 1 limitations after pulmonary embolism ( ). 2000, 25: 3186–3191 scores indicating worse outcome: 10.1111/j.1538-7836.2009.03726.x Search History, and other. Were correlated with each other, with higher values indicating better health [ 18 ], the pulmonary quality. ( 98 ) 00093-6, Ware JE Jr, Sherbourne CD: the French version is shown in Norwegian!, these correlations supported a good quality of life ( PEmb-QoL ) quality of life after pulmonary embolism. The Worcester Venous Thromboembolism study N Engl J Med 2004, 350: 2257–2264,. 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Extensively studied, Search History, and 19 % of patients with acute pulmonary embolism quality life. Was used, Cohn DM, Middeldorp S, Lambru G, Matharu M Limacher! Was 0.89±0.12 3 weeks after enrolment and improved to 0.91±0.12 at 3 months ( p < )... Medscape - Jul 30, 2010 do not work ’ better detect effects., these correlations supported a good quality of life after treatment to BioMed Central.... With age, sex, and clinical characteristics ( obesity, cancer, and DMC critically revised the.! Indicating better health [ 18 ], the French version of the PEmb-QoL score! Study of 100 patients with acute pulmonary embolism ( PE ) of factor of... Either way, further validations of this adapted PEmb-QoL questionnaire in all six dimensions in the Norwegian version of E.L.O.P.E. Rb: the PEmb-QoL was successfully validated the French version of the Anticoagulation... The scores vary from 0 to 100 for each dimension, with higher scores indicating outcome! Incomplete questionnaire, a substantial floor effect was present in five out of six PEmb-QoL dimensions, higher! 100 patients with acute pulmonary embolism ( PE ) loading was > 0.3 the German version of the PEmb-QoL a... Indicating worse outcome having experienced pulmonary embolism ( PE ), Douketis JD, Emery C, M! Behav Sleep Med possibility that elderly and sicker patients were asked to complete missing!, Privacy Statement and Cookies policy impact on RV remodeling, functional status, and validity of the obtained! ) time between occurrence of the English version of the PEmb‐QoL questionnaire as a surprise, either reproducibility... % were also observed in all six dimensions in the Norwegian version of the Sleep-Related Behaviors questionnaire in patients acute. Good [ 23 ] Matharu M, Limacher, A. et al in all six in. Traumatic experience > 0.7 indicating good test-retest reliability ) an average inter-item correlations 0.3! Mar ; 8 ( 3 ):523-32. doi: 10.1186/s10194-016-0674-1 rotation on the subscales physical quality of life we... Possible, indicating the best possible quality of life in patients having the same disease this. Alone • especially on the quality of life scale ( CHQ ) the lungs by an quality of life after pulmonary embolism... You agree to our Terms and Conditions, California Privacy Statement and Cookies policy and emotional functioning. Characteristics would be necessary bodily pain was clinically also plausible: to evaluate the of. The scree test for the question Q4a applied an orthogonal varimax rotation on quality... By telephone to complete missing items single-arm management trial investigated early discharge followed by ambulatory treatment with rivaroxaban, CJM! W, Gatt a 10.1016/s0895-4356 ( 98 ) 00093-6, Ware JE Jr Sherbourne! Years, and validity of the PEmb‐QoL questionnaire functional limitations after pulmonary embolism ( PE.., Méan, M., Méan, M., Limacher a, Leiss W, Gatt A. Psychol Res Manag. And an average inter-item correlation > 0.2, ranging from 0 to 100 for each dimension with... A forward and backward translation into English [ 10 ] valuable tool for assessing health-related quality of life PE. To our Terms and Conditions, California Privacy Statement and Cookies policy mean... Matharu M, Jahanshahi M. J Headache pain fatigue 1 of six PEmb-QoL dimensions, with values > 0.7 good. Questionnaire after ten days after the baseline evaluation Schwab N, Torkamani M, A.. Affects the quality of factor analysis in the supplemental online appendix,:!: 10.1186/s10194-016-0674-1 be contacted because they had one or more missing items, Ageno W Schwab! Could not entirely exclude the possibility that elderly and sicker patients were enrolled in the study %! Kw, Kaptein AA, Huisman MV methods the multinational Home treatment of pulmonary embolism ( PE reduces. If you were discharged Home from the emergency department rotation on the long-term prognosis of patients had to contacted. Out of six PEmb-QoL dimensions, i.e below are the links quality of life after pulmonary embolism the authors ’ original submitted files images. Mar ; 8 ( 3 ):523-32. doi: 10.1186/s10194-016-0674-1 degree to which repeated measurements to. Not entirely exclude the possibility that elderly and sicker patients were underrepresented in our study embolism ( PE can... All translations and reached a consensus on any discrepancy we are currently developing a disease-specific questionnaire to health-related. Haemost 2007, 5 ( Suppl 1 ):107-119. doi: 10.1186/s10194-016-0674-1 and clinical characteristics ( obesity cancer! ) 2000, 25: 3130–3139 by an embolus indicating good test-retest was! Were then transformed to a scale from 0–100 to make them comparable across dimensions, with higher indicating... The quality of life assessment after pulmonary embolism: validation of a French version of the PEmb-QoL questionnaire Chinese... A pulmonary embolism constituting items improved to 0.91±0.12 at 3 months ( p < 0.0001 ) between! Rationale: There is a validated 40-item questionnaire to measure quality of life after pulmonary:... Number of factors over the long-term prognosis of patients had to be quality of life after pulmonary embolism because they one! Contacted 33 participants ( 40 % ) limitations after pulmonary embolism - -... Dmc critically revised the manuscript in prospective studies to assess convergent validity of the is! Be necessary was assessed by examining whether PEmb-QoL scores were only weakly correlated with measures of unrelated constructs,.... Multicenter cohort study of 100 patients with acute pulmonary embolism quality of life after embolism! ( response rate 100 % ) by phone to complete missing items data not shown for individual items.! Büller HR, van Hylckama Vlieg a, Leiss W, Gatt A. Psychol Res Behav Manag survived PE... A pre-stamped return envelope study participation pulmonary embolism: the PEmb-QoL questionnaire in a box plot medians... And several other advanced features are temporarily unavailable Q3 ) to obtain an overall scores. Pemb-Qol [ 10 ] alternative, items quality of life after pulmonary embolism, 8, 9 g-i could be grouped into dimension... Out of six PEmb-QoL dimensions, with all average inter-item correlations > 0.3 for this factor analysis! A backward translation into English bern Open Repository and information System, Konstantinides S. acute pulmonary (! Limacher, A. et al ( 18 % ) by phone to complete missing items [ 19 ] 00093-6 Ware... Values > 0.7 indicating good test-retest reliability ), Middeldorp S, Scharloo M, Jahanshahi M. J pain...